Retropubic versus Transobturator Midurethral Slings for Stress ...

More vaginal perforations occurred in the transobturator-sling group than in the retropubic-sling group (13 vs. 6); the majority of those in the transobturator-sling group occurred when the in-to-out approach was used (10). ...

Human Parvovirus B19–Associated Myocarditis — NEJM

we measured viral loads in endomyocardial biopsy specimens obtained from 498 patients (341 men and 157 women; mean [±SD] age, 46.93±15.85 years) with myocarditis2 or chronic dilated cardiomyopathy who were positive for parvovirus B19 on ... As shown in Figure 1B, acute parvovirus B19–associated myocarditis was characterized by a high mean viral load of 316000 genome equivalents (ge) per microgram of isolated nucleic acids, whereas the mean viral load of 709 ge per ...

Cardiac-Resynchronization Therapy — NEJM

Correspondence from The New England Journal of Medicine — Cardiac-Resynchronization Therapy.

COMT Val158Met Genotype as a Risk Factor for Problem Behaviors in ...

Authors: Albaugh MD, Harder VS, Althoff RR, Rettew DC, Ehli EA, Lengyel-Nelson T, Davies GE, Ayer L, Sulman J, Stanger C, Hudziak JJ. OBJECTIVE: To test the association between the catechol-O-methyltransferase (COMT) Val158Met ...

Benazepril plus Amlodipine or Hydrochlorothiazide for Hypertension ...

GE Bartsch, SK Broste, GA Grandits, RH Grimm, JD Neaton, KH SvendesnHydrochlorothiazide, chlorthalidone and mortality in the Multiple Risk Factor Intervention Trial.. Circulation 1984;70:Suppl II:II-360 ... Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).. JAMA 2002;288:2981-2997[Erratum, ...

Cumulative Association of Five Genetic Variants with Prostate ...

S. Lilly Zheng, M.D., Jielin Sun, Ph.D., Fredrik Wiklund, Ph.D., Shelly Smith, M.S., Pär Stattin, M.D., Ph.D., Ge Li, M.D., Hans-Olov Adami, M.D., Ph.D., Fang-Chi Hsu, Ph.D., Yi Zhu, B.S., Katarina Bälter, Ph.D., A. Karim Kader, M.D., .... Case subjects were classified as having advanced disease if they met any of the following criteria: a grade 3 or 4 tumor, spread to nearby lymph nodes and metastasis, a Gleason score of 8 or more, or a PSA level of more than 50 ng per ...

B-Cell Clones as Early Markers for Chronic Lymphocytic Leukemia — NEJM

Among 43 patients with available information on Rai staging of disease (ranging from 0 [low risk] to I or II [intermediate risk] to III or IV [high risk]) at the time of the diagnosis of CLL, 40 patients (93%) had stage 0 or I, 2 patients ( 5%) had ..... In: Marti GE, Vogt RF, Zenger VE, eds. Proceedings of the USPHS workshop on laboratory approaches to determining the role of environmental exposures as risk factors for B-cell chronic lymphocytic leukemia and other B-cell ...

Acyclovir and Transmission of HIV-1 from Persons Infected with HIV ...

The inclusion criteria for partners infected with HIV-1 were an age of at least 18 years, seropositivity for HIV-1 and HSV-2, a CD4 count of 250 or more cells per cubic millimeter, no conditions associated with acquired immunodeficiency ...

Apixaban or Enoxaparin for Thromboprophylaxis — NEJM

The timing of the first apixaban administration (a mean [±SD] of 20.3±3.5 hours postoperatively in the Apixaban Dose Orally vs. Anticoagulation with Enoxaparin 2 [ADVANCE-1] study; ClinicalTrials.gov number, NCT00371683) or the total daily dose could affect the ... MR Lassen, GE Raskob, A Gallus, G Pineo, D Chen, RJ PortmanApixaban or enoxaparin for thromboprophylaxis after knee replacement.. N Engl J Med 2009;361:594-604. Free Full Text | Web of Science | Medline ...

A Randomized, Controlled Trial of Financial Incentives for Smoking ...

The rate of participation in a smoking-cessation program was significantly higher in the incentive group than in the control group (15.4% vs. 5.4%, P